Takeda bets $4B upfront on Nimbus’ phase 3-ready prospect to challenge Bristol Myers in psoriasis

Nimbus Therapeutics’ midphase psoriasis data have persuaded Takeda that the biotech’s TYK2 inhibitor will be big. How big? $4 billion upfront and more again on the back end. Late last month, Nimbus presented top-line findings from a phase 2b clinical trial of NDI-034858, using the update to repeat its claim that the rival to Bristol Myers Squibb’s Sotyktu has best-in-class potential. The update lacked figures to back up the claim, but Takeda’s decision to bet big on the candidate shortly after the data drop hints at how strong a hand Nimbus is holding.